Zani 2004.

Methods	Design: parallel group randomized trial Duration of study: March 2001 to March 2002 Follow‐up: 30 days
Participants	Country: Brazil Setting: community Number included in study: 151 Age: 2–82 years Sex: not reported Inclusion criteria: people positive for A lumbricoides,T trichiura, or hookworms Exclusion criteria: pregnant or lactating women, children aged < 2 years, and people with intense infection involving expulsion of worms through the mouth and faeces, did not receive any medication Number positive for A lumbricoides: 83 Number included in review: 83
Interventions	Treatment strategy: screened, randomized and treated all included participants Group 1: mebendazole 100 mg twice a day over 3 consecutive days (n = 41) Group 2: albendazole 400 mg single dose (n = 42) Participants positive for S mansoni were treated with praziquantel (60 mg/kg, Farmanguinhos/Fiocruz, 1 week after the treatment for helminthiasis)
Outcomes	Outcomes included:Ascaris prevalence pre‐ and post‐treatment, cure rates Outcomes not included in review: anthelmintic efficacy for Trichuris, hookworm
Notes	Diagnostic technique: Kato‐Katz Funding support: World Health Organization
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "Each group was randomly assigned to treatment with one or the other anthelmintic drug."
Allocation concealment (selection bias)	Unclear risk	Details not reported.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Different treatment schedule.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Details not reported.
Incomplete outcome data (attrition bias) All outcomes	High risk	32 (21.2%) participants lost at follow‐up and not included in analysis.
Selective reporting (reporting bias)	High risk	Adverse events not reported.
Other bias	Low risk	No obvious source of other bias.

A lumbricoides:Ascaris lumbricoides; AM: arithmetic mean; epg: eggs per gram; ERR: egg reduction rate; GM: geometric mean; n: number of participants; S mansoni: Schistosoma mansoni; T trichiura:Trichuris trichiura;W bancrofti: Wuchereria bancrofti.