Skip to main content
. 2020 Apr 14;2020(4):CD010599. doi: 10.1002/14651858.CD010599.pub2

TCTR20190111001.

Trial name or title Assessment of efficacy of anthelmintic drugs against soil‐transmitted helminths in Thailand
Methods Randomized trial (TCTR20190111001)
Participants Number of participants: 252
Inclusion criteria
  • Age: 18–70 years

  • Infected with any of Ascaris, hookworms, Trichuris, or Strongyloides)


Exclusion criteria
  • History of acute or severe chronic

  • Pregnant or lactating

  • Vomited within 4 hours after drug administration

  • Unable to provide a stool sample at follow‐up

  • History of allergic reaction to albendazole, mebendazole, or ivermectin

Interventions
  • Group 1: albendazole 400 mg single dose

  • Group 2: albendazole 400 mg twice daily for 3 days

  • Group 3: ivermectin 200 μg/kg single dose

  • Group 4: mebendazole 100 mg twice daily for 3 days

  • Group 5: albendazole 400 mg single dose + ivermectin 200 μg/kg single dose

  • Group 6: mebendazole 500 mg single dose + ivermectin 200 μg/kg single dose

Outcomes Cure rate 3 weeks after treatment
Egg reduction rate
Modified Kato‐Katz thick smear, Harada‐mori
Starting date Not reported
Contact information Vivornpun Sanprasert
Department of Parasitology, Faculty of Medicine, Chulalongkorn University 1873 Rama IV Road, Pathumwa, Bangkok 10330, Thailand
Notes Funding: Department of Parasitology, Faculty of Medicine, Chulalongkorn University 1873 Rama IV Road, Pathumwa, Bangkok, 10330, Thailand
+6622564387 17; vivornpun@chula.md