Table 1.
Physicochemical parameters of SARS-CoV-2 3CLpro.
| Parameters | SARS-CoV-2 3CLpro |
|---|---|
| Mol. Weight | 33796.64 Dalton |
| No. of amino acids | 306 |
| Theoretical pI | 5.95 |
| Instability index (II) | 27.65 (stable) |
| No. of negatively charged residues (Asp + Glu) | 26 |
| No. of positively charged residues (Arg + Lys) | 22 |
| Aliphatic index | 82.12 |
| Grand average of hydropathicity (GRAVY) | −0.019 |
| Atomic composition | Carbon-1499; Hydrogen-2318; Nitrogen-402; Oxygen-445; Sulfur-22 |
| Amino acid composition | Ala-17 (5.6%); Arg-11 (3.6%); Asn-21 (6.9%); Asp-17 (5.6%); Cys-12 (3.9%); Gln-14 (4.6%); Glu-9 (2.9%); Gly-26 (8.5%); His-7 (2.3%); Ile-11 (3.6%); Leu-29 (9.5%); Lys-11 (3.6%); Met-10 (3.3%); Phe-17 (5.6%); Pro-13 (4.2%); Ser-16 (5.2%); Thr-24 (7.8%); Trp-3 (1.0%); Tyr-11 (3.6%); Val-27 (8.8%); Pyl-0 (0.0%); Sec-0 (0.0%) |