Table 1. List of proteins containing ubiquitin binding domain that are described or predicted to bind to ubiquitinated FANCD2.
Protein | Function | Domain | Reference |
---|---|---|---|
FAN1 | Nuclease | UBZ4 | (Kratz et al., 2010) |
SLX4 | Nuclease | UBZ1 | (Lachaud et al., 2014) |
FAAP20 | FANCA partner | UBZ | (Hein et al., 2015) |
RAP80 | BRCA1 partner | UIM | (Castillo et al., 2014) |
SMARCAD1 | Chromatin remodeler | CUE | (Densham et al., 2016) |
FANCJ | Helicase | - | (Raghunandan et al., 2015) |
PSMD4 | Protease | UIM | (Jacquemont and Taniguchi, 2007) |
SF3B1 | RNA binding protein | UBZ | (Moriel-Carretero et al., 2017) |
TRIM25 | E3 ligase | RING finger | (Lossaint et al., 2013) |
MCM5 | CMG component | - | (Lossaint et al., 2013) |
BRE | BRCA1 partner | - | (Wang, 2007) |
BRCC | BRCA1 partner | - | (Wang, 2007) |
SNM1A | Nuclease | UBZ | (Yang et al., 2010) |
CtIP* | Nuclease activator | C2H2 zinc finger | (Murina et al., 2014) |
Rev1* | Translesion polymerase | UBZ3 | (Moldovan et al., 2010) |
*Indicates not tested in our experiments, because protein not produced in TnT system.