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Half Maximal Inhibitory Concentrations (IC50) of Sor/CR, Fulvestrant, TIPT, and Miconazole Colloids Against TEM-1 Stability Mutants
| mutant | Sor/CR (μM) | Fulvestrant (μM) | TIPT (μM) | Miconazole (μM) |
|---|---|---|---|---|
| M182T | 710 ± 37 | 78.4 ± 14.3 | 4.7 ± 0.2 | 130 ± 9.3 |
| M182T/G238S | 21.4 ± 0.3 | 17.6 ± 1.9 | 0.92 ± 0.1 | 58.2 ± 17.6 |
| WT | 629 ± 29 | 55.9 ± 12.3 | 3.4 ± 0.3 | 125 ± 7.9 |
| R164S | 141 ± 13 | 35.8 ± 2.5 | 1.7 ± 0.2 | 95.3 ± 6.9 |
| G238S | 18.8 ± 1.6 | 13.1 ± 0.7 | 0.88 ± 0.1 | 52.8 ± 7.9 |
| D179G | ||||
