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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Curr Opin Struct Biol. 2019 Nov 18;61:17–24. doi: 10.1016/j.sbi.2019.10.001

Figure 1.

Figure 1

Cryo-EM structures of TFIID and its binding to DNA. (a) Cryo-EM reconstruction of human TFIID bound to promoter DNA. The promoter elements in the SCP are highlighted. (b) Cryo-EM reconstructions of TFIID, with a transparent outline of TFIID in a canonical state and fitted cryo-EM maps from focused refinements of the BC core and Lobe A, colored by subunit following the code shown at the bottom of figure. (c) Atomic model of human TFIID using the same subunit color code.