Table 2.

Hazard ratios and corresponding 95% confidence intervals from internally estimated stratified Cox regression models for time to first ASCVD event relative to study baseline. Separate models were estimated for each age category. Hazard ratios associated with patient sex are not included due to the fact that the models incorporated separate baseline hazard functions for males and females (baseline 5-year cumulative hazard estimates are provided in the Appendix)

		Age at Study Baseline
Parameter	Level	65–74 Years	75–84 Years	≥85 Years
Age (per 5 years)		1.36 [1.23, 1.50]	1.38 [1.24, 1.52]	1.47 [1.26, 1.71]
African American race		1.51 [1.31, 1.74]	1.11 [0.94, 1.31]	1.13 [0.87, 1.46]
Total Cholesterol	≤150 mg/dL	Reference	Reference	Reference
	151–200 mg/dL	0.75 [0.66, 0.86]	0.93 [0.82, 1.06]	0.71 [0.57, 0.87]
	201–250 mg/dL	0.70 [0.59, 0.83]	0.80 [0.67, 0.95]	0.65 [0.50, 0.86]
	>250 mg/dL	0.78 [0.57, 1.07]	1.04 [0.76, 1.41]	0.74 [0.44, 1.24]
HDL Cholesterol	≤40 mg/dL	1.35 [1.13, 1.60]	1.39 [1.15, 1.67]	1.44 [1.08, 1.93]
	41–50 mg/dL	1.05 [0.90, 1.24]	1.18 [1.01, 1.40]	1.08 [0.83, 1.41]
	51–60 mg/dL	Reference	Reference	Reference
	>60 mg/dL	0.83 [0.70, 0.97]	0.98 [0.84, 1.15]	0.96 [0.76, 1.23]
Systolic Blood Pressure	≤120 mmHg	1.16 [1.00, 1.36]	1.04 [0.89, 1.22]	1.13 [0.88, 1.46]
	121–130 mmHg	Reference	Reference	Reference
	131–140 mmHg	1.06 [0.91, 1.25]	0.92 [0.78, 1.07]	1.09 [0.85, 1.39]
	>140 mmHg	1.32 [1.13, 1.55]	1.06 [0.91, 1.24]	1.07 [0.83, 1.37]
Antihypertensive use		1.62 [1.38, 1.90]	1.52 [1.28, 1.80]	1.42 [1.05, 1.93]
Type II diabetes mellitus		1.50 [1.33, 1.70]	1.20 [1.06, 1.37]	1.03 [0.83, 1.30]
Current smoking		1.70 [1.45, 1.98]	1.40 [1.13, 1.73]	2.14 [1.43, 3.19]