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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Shock. 2020 Sep;54(3):330–336. doi: 10.1097/SHK.0000000000001463

FIG. 5. Jejunal immunohistochemistry of TJ following CLP.

FIG. 5

Claudin 3 is distributed equally along the crypt-villus axis and staining is more dense in WT mice than Fabp-Bcl-2 mice. Claudin 5 stains more prominently throughout the crypt and base of the villus and is also more prominent in WT mice. Claudin 4 staining is present in spotty areas throughout the crypt and villus of WT mice. This does not change in prominence in transgenic mice; however, staining is more prominent in the lamina propria of Fabp-Bcl-2 mice. Occludin is not detectable in WT mice. Occludin stains heavily in isolated villus cells and intervillus cells in Fabpl-Bcl-2 cells. Representative histomicrographs are shown of n=4 mice/group examined