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. 2020 Apr 14;10:6395. doi: 10.1038/s41598-020-63148-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Functional enrichment of survival-associated IRGs. Survival-associated IRGs identified via Gene Ontology (GO) analysis (a) and KEGG pathway analysis (b). Circle graphs representing the most significant Gene Ontology terms (c) and Kyoto Encyclopedia of Genes and Genomes pathways (d). Nodes in the concentric circle graph represent co-expressed genes clustered in specific biological process terms. The inner sectors with larger size and darker color represent more significant enrichment. Heat maps representing the overall expression levels of 20 enriched Gene Ontology terms (e) and Kyoto Encyclopedia of Genes and Genomes pathways (f).