Fig. 1. The BRCA1 promoter regions assessed for methylation by the studies listed in Table 1.

The number(s) in each bar corresponds to the study number (#) in Table 1. The BRCA1 promoter region assessed by each study is represented by a horizontal bar. Black bars represent studies that measured BRCA1 promoter methylation in blood-derived DNA. White bars represent studies that measured BRCA1 promoter methylation in blood-derived DNA and DNA derived from sources other than blood. Each CpG dinucleotide is represented as a vertical line and numbered relative to the BRCA1 transcription start site (denoted by +1).