Table 2.
Metastats analysis.
| OTU | Classificationa | Mean abundance (%) | Metastats P value | |||||
|---|---|---|---|---|---|---|---|---|
| According to RDP database | According to Greengenes database | Healthy | SIV infected | c-ART treated | Healthy vs SIV infected | SIV infected vs c-ART treated | Healthy vs c-ART treated | |
| OTU2 | Streptococcus | Streptococcus luteciae | 1.44 | 3.49 | 4.95 | 0.215 | 0.620 | 0.034 |
| OTU3 | Porphyromonadaceae (family) | S24-7 (family) | 1.60 | 2.12 | 3.53 | 0.707 | 0.379 | 0.048 |
| OTU4 | Prevotella | Prevotella copri | 3.82 | 0.40 | 1.91 | 0.001 | 0.002 | 0.071 |
| OTU6 | Acinetobacter | Acinetobacter | 0.10 | 4.65 | 1.66 | 0.059 | 0.286 | 0.008 |
| OTU7 | Treponema | Treponema | 0.71 | 7.51 | 0.14 | 0.068 | 0.052 | 0.008 |
| OTU8 | Prevotella | Prevotella copri | 2.29 | 0.50 | 2.51 | 0.007 | 0.002 | 0.852 |
| OTU10 | Treponema | Treponema | 0.43 | 3.98 | 1.06 | 0.076 | 0.178 | 0.042 |
| OTU11 | Prevotella | Prevotella copri | 2.00 | 0.05 | 2.61 | 0.040 | 0.013 | 0.753 |
| OTU13 | Treponema | Treponema | 2.04 | 0.06 | 1.68 | 0.044 | 0.086 | 0.848 |
| OTU14 | Bacteroidetes (phylum) | p-2534-18B5 (family) | 0.48 | 1.04 | 2.14 | 0.335 | 0.215 | 0.017 |
| OTU15 | Prevotellaceae (family) | [Prevotella] | 1.36 | 0.63 | 1.70 | 0.282 | 0.037 | 0.723 |
| OTU19 | Lactobacillus | Lactobacillus | 1.16 | 1.62 | 0.22 | 0.668 | 0.007 | 0.106 |
| OTU23 | Treponema | Treponema | 0.70 | 2.68 | 0.08 | 0.259 | 0.108 | 0.038 |
| OTU25 | Dialister | Dialister | 1.42 | 0.40 | 0.73 | 0.012 | 0.122 | 0.110 |
| OTU27 | Bacteroidales (order) | YRC22 | 1.81 | 0.36 | 0.33 | 0.041 | 0.899 | 0.036 |
| OTU33 | Enterobacteriaceae (family) | Enterobacteriaceae (family) | 0.05 | 1.19 | 0.79 | 0.096 | 0.728 | 0.030 |
| OTU37 | Bacteroidetes (phylum) | Bacteroidetes (phylum) | 0.15 | 0.27 | 1.04 | 0.476 | 0.020 | 0.005 |
| OTU42 | Bacteria (kingdom) | Treponema | 1.10 | 0.13 | 0.04 | 0.010 | 0.629 | 0.004 |
| OTU54 | Lactobacillus | Lactobacillus | 0.17 | 1.07 | 0.02 | 0.031 | 0.013 | 0.017 |
OTU number is listed, together with the classification according to the Ribosomal Database Project (RDP) and the Greengenes databases. OTUs constituting ≥1% mean abundance for any group (healthy, SIV infected, or c-ART treated) are shown. Analysis was performed from a subsampled dataset. Metastats P values < 0.05 are shown in bold. aGenus and species are italicized. If the OTU was not classified to genus, the taxonomic group to which it classified is listed, with that taxonomic level in parantheses. No species information was available for OTUs classified to the RDP collection.