Table 1.

Differentially expressed proteins in androgen dependent and androgen independent prostate cancer cell lines identified using SWATH-LC-MS/MS.

S.No	Protein (Human)	UNIProt ID	Protein Name	Occurrence	Contribution
1	GOT1	P17174	Aspartate aminotransferase	LNCaP PC-3	GO-MF: carboxylic acid binding; GO-MF: phophatidyl decarboxylase activity; GO-MF: pyridoxal phosphate binding; GO-BP: aspartate metabolic process; GO-BP: gluconeogenesis; GO-BP: notch signaling; GO-BP: transdifferentiation
2	HNRNPA2B1	P22626	Heterogeneous nuclear ribonucleoproteins A2/B1	LNCaP	GO-MF: protein binding; GO-MF: mRNA binding; GO-MF: N6-methyladenosine containing RNA binding; GO-BP: miRNA transport; GO-BP: mRNA processing; GO-BP: RNA transport; GO-BP: telomere maintenance
3	MAPK1	P28482	Mitogen-activated protein kinase 1	PC-3	GO-MF: ATP binding; GO-MF: kinase activity; GO-MF: phosphatase binding; GO-MF: transcription factor binding; GO-BP: activation of MAPK activity; GO-BP: cell cycle; GO-BP: cellular response to DNA damage; GO-BP: response to tumor necrosis; GO-BP: response to reactive oxygen species
4	PAK2	Q13177	Serine/threonine-protein kinase PAK2	PC-3	GO-MF: ATP binding; GO-MF: cadherin binding; GO-MF: protein kinase binding; GO-MF: protein tyrosine kinase activator activity; GO-BP: apoptotic process; GO-BP: cell migration; GO-BP: protein phosphorylation; GO-BP: MAPK cascade; GO-BP: T cell receptor signaling
5	UBE2N	P61088	Ubiquitin-conjugating enzyme E2 N	LNCaP PC-3	GO-MF: ATP binding; GO-MF: ubiquitin protein ligase binding; GO-MF: ubiquitin-protein transferase activity; GO-BP: MAPK activity; GO-BP: protein modification; GO-BP: DNA and post replication repair; GO-BP: T cell receptor signaling
6	YWHAB	P31946	14-3-3 protein beta/alpha	LNCaP; PC-3	GO-MF: cadherin binding, GO-MF: histone deacetylase binding; GO-MF: protein-domain specific binding; GO-BP: hippo signaling; GO-BP: MAPK cascade; GO-BP: regulation of G protein-coupled receptor; GO-BP: transcriptional regulation; GO-BP: protein targeting