Table 2.
Dosimetric comparison between the scalp of the patients who did not develop alopecia and the scalp of the patients who developed G1 or G2 alopecia at the end of radiotherapy: mean values and standard deviations (in brackets) of dosimetric variables.
| n | Mean D0.1cc (Gy) | Mean Dmean (Gy) | Mean V16Gy (cc) | Mean V20Gy (cc) | Mean V25Gy (cc) | Mean V30Gy (cc) | Mean V35Gy (cc) | Mean V40Gy (cc) | Mean V43Gy (cc) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Scalppatients no alopecia | 5 | 19.7 (± 12.6) | 3.1 (± 1.5) | 2.7 (± 3.7) | 1.4 (± 1.9) | 0.6 (± 1.1) | 0.2 (± 0.5) | 0.04 (± 0.09) | 0 | 0 |
| Scalppatients with G1 alopecia at the end of RT | 11 | 40.2 (± 15.2) | 10.6 (± 5.0) | 45.2 (± 40.4) | 31.0 (± 33.9) | 22.2 (± 26.9) | 15.6 (± 20.5) | 10.8 (± 15.6) | 7.4 (± 12.1) | 5.8 (± 10.0) |
| p-value from Mann–Whitney Test | 0.02 | 0.001 | 0.002 | 0.02 | 0.03 | 0.04 | 0.90 | 0.90 | 0.09 | |
| Scalppatients with G2 alopecia at the end of RT | 85 | 47.3 (± 9.2) | 11.8 (± 4.4) | 68.8 (± 37.7) | 50.6 (± 33.4) | 34.8 (± 27.5) | 23.1 (± 22.0) | 14.3 (± 16.9) | 8.4 (± 12.0) | 5.9 (± 9.3) |
| p-value from Mann-Whitney Test | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.001 | 0.004 | 0.005 | |
D0.1cc, dose received by 0.1 cc; Dmean, mean dose; VxGy, percentage of the scalp volume receiving ≥ x Gy.
Bold text indicates statistical significance.