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. 2020 Apr 8;10:467. doi: 10.3389/fonc.2020.00467

Table 6.

Receiver operating characteristics (ROC) analysis for G2 alopecia at 9 months after the end of radiotherapy.

Dosimetric variable AUC p-value for AUC Cut-off Sensitivity, % Specificity, % Incidence of G2 alopecia at 9 months Fisher exact test p-value
Low risk, % High risk, %
D0.1cc 0.684 0.008 47.6 Gy 100.00 51.5 0.0% 17.4% 0.007
Mean dose 0.669 0.04 10.1 Gy 100.00 43.9 0.0% 14.0% 0.02
V30Gy 0.662 0.04 11.4 cc 100.00 39.4 0.0% 13.1% 0.04
V35Gy 0.710 0.001 9.3 cc 100.00 54.5 0.0% 17.4% 0.005
V40Gy 0.738 <0.0001 5.4 cc 100.00 63.64 0.0% 21.0% 0.0000
V43Gy 0.725 0.0002 2.2 cc 100.00 59.1 0.0% 19.5% 0.001

D0.1cc, Dose to 0.1 cc of the scalp volume;VxGy, percentage of the scalp volume receiving ≥ x Gy; AUC, area under curve at ROC analysis.

Bold text indicates statistical significance.