Table 6.
Receiver operating characteristics (ROC) analysis for G2 alopecia at 9 months after the end of radiotherapy.
Dosimetric variable | AUC | p-value for AUC | Cut-off | Sensitivity, % | Specificity, % | Incidence of G2 alopecia at 9 months | Fisher exact test p-value | |
---|---|---|---|---|---|---|---|---|
Low risk, % | High risk, % | |||||||
D0.1cc | 0.684 | 0.008 | 47.6 Gy | 100.00 | 51.5 | 0.0% | 17.4% | 0.007 |
Mean dose | 0.669 | 0.04 | 10.1 Gy | 100.00 | 43.9 | 0.0% | 14.0% | 0.02 |
V30Gy | 0.662 | 0.04 | 11.4 cc | 100.00 | 39.4 | 0.0% | 13.1% | 0.04 |
V35Gy | 0.710 | 0.001 | 9.3 cc | 100.00 | 54.5 | 0.0% | 17.4% | 0.005 |
V40Gy | 0.738 | <0.0001 | 5.4 cc | 100.00 | 63.64 | 0.0% | 21.0% | 0.0000 |
V43Gy | 0.725 | 0.0002 | 2.2 cc | 100.00 | 59.1 | 0.0% | 19.5% | 0.001 |
D0.1cc, Dose to 0.1 cc of the scalp volume;VxGy, percentage of the scalp volume receiving ≥ x Gy; AUC, area under curve at ROC analysis.
Bold text indicates statistical significance.