Table 4.

Effect of crude ethanolic extract (CEX) on the appearance of gastric lesions induced by HCl/EtOH (p.o.) in Indomethacin- (IND), N-ethylmaleimide- (NEM), and N-nitro-L-arginine methyl ester- (L-NAME) pretreated mice.

Treatment	Dose (mg/kg)	Lesion index (mm)
Control	–	41.6 ± 4.9
IND	10	36.0 ± 3.8
NEM	10	38.6 ± 4.4
L-NAME	70	40.7 ± 5.1
CEX	50	16.7 ± 3.5*
IND + CEX	10 + 50	35.9 ± 2.8
NEM + CEX	10 + 50	37.7 ± 5.3
L-NAME + CEX	70 + 50	18.0 ± 3.1*
Carbenoxolone	100	14.6 ± 4.2*

Results are expressed as mean ± SD, n = 7. Analysis of variance followed by Dunnett’s test. *P < 0.01 compared with the respective control.

IND, Indomethacin; NEM, N-ethylmaleimide; L-NAME, N-nitro-L-arginine methyl ester.