Table 1.
Baseline demographic and clinical characteristics of natural vs. programming cycle.
| Natural cycle (n = 10, 211) | Programming cycle (n = 4,162) | P | |
|---|---|---|---|
| Maternal age (years) | 30.93 ± 4.16 | 30.63 ± 4.14 | <0.001 |
| Paternal age (years) | 31.46 ± 4.78 | 31.25 ± 4.81 | 0.020 |
| Baseline systolic pressure (mmHg) | 119.36 ± 11.40 | 120.40 ± 10.98 | <0.001 |
| Baseline diastolic pressure (mmHg) | 77.45 ± 8.65 | 78.20 ± 8.02 | <0.001 |
| Baseline BMI (kg/m2) | 22.68 ± 3.20 | 23.30 ± 3.41 | <0.001 |
| Baseline BMI (%) | |||
| <18.5 | 700 (6.9) | 231 (5.6) | <0.001 |
| 18.5–23.9 | 6,405 (62.7) | 2,325 (55.9) | |
| 24.0–27.9 | 2,382 (23.3) | 1,190 (28.6) | |
| ≥28 | 724 (7.1) | 416 (10.0) | |
| Nulliparity (%) | 5,757 (56.4) | 2,312 (55.6) | 0.363 |
| Cause of infertility (%) | |||
| Pelvic factor | 7,043 (69.0) | 2,872 (69.0) | 0.102 |
| Male factor | 2,785 (27.3) | 1,103 (26.5) | |
| Unexplained infertility | 167 (1.6) | 72 (1.7) | |
| Others | 216 (2.1) | 115 (2.8) | |
| Proportion of IVF (%) | 7,196 (70.5) | 2,967 (71.3) | 0.330 |
| Baseline FSH (IU/L) | 6.58 ± 1.65 | 6.37 ± 1.63 | <0.001 |
| Baseline LH(IU/L) | 4.96 ± 2.06 | 5.33 ± 2.67 | <0.001 |
| Baseline T (n/dL) | 24.71 ± 11.54 | 27.03 ± 12.45 | <0.001 |
| AFC | 13.85 ± 5.37 | 14.70 ± 6.06 | <0.001 |
| Baseline fasting glucose (mmol/L) | 5.22 ± 0.50 | 5.27 ± 0.50 | <0.001 |
| Number of embryos transferred | 1.16 ± 0.37 | 1.18 ± 0.39 | 0.005 |
| Endometrial thickness in FET (cm) | 1.02 ± 0.16 | 0.94 ± 0.14 | <0.001 |
BMI, body mass index; IVF, in vitro fertilization; FSH, follicle-stimulating hormone; LH, luteinizing hormone; T, total testosterone; AFC, number of antral follicle count; FET, frozen embryo transfer.