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. 2020 Apr 8;7:104. doi: 10.3389/fmed.2020.00104

Table 2.

Obstetric and perinatal outcomes of natural vs. programming cycle.

Natural cycle (n = 10,211) Programming cycle (n = 4,162) P
Pre-eclampsia (%) 393 (3.8) 356 (8.6) <0.001
GDM (%) 575 (5.6) 259 (6.2) 0.169
Placenta previa (%) 77 (0.8) 39 (0.9) 0.266
Placental abruption (%) 10 (0.1) 9 (0.2) 0.077
Postpartum hemorrhage (%) 17 (0.2) 29 (0.7) <0.001
Cesarean section (%) 7,091 (69.4) 3,360 (80.7) <0.001
Gestational age at delivery (weeks) 39.15 ± 1.55 39.10 ± 1.74 0.099
Preterm labor (%) 581 (5.7) 315 (7.6) <0.001
Post-term birth (%) 26 (0.3) 14 (0.3) 0.399
Average birthweight (g) 3455.6 ± 500.6 3459.7 ± 537.5 0.673
Male sex of neonates (%) 5,440 (53.3) 2,227 (53.5) 0.800
Macrosomia (%) 1,032 (10.1) 433 (10.4) 0.594
LBW (%) 296 (2.9) 141 (3.4) 0.121
VLBW (%) 39 (0.4) 26 (0.6) 0.049
LGA (%) 1,987 (19.5) 855 (20.5) 0.139
SGA (%) 516 (5.1) 226 (5.4) 0.355

GDM, gestational diabetes mellitus; LBW, low birthweight; VLBW, very low birthweight; LGA, large for gestational age; SGA, small for gestational age.