Table 3.
Incidence rates and adjusted HR of stroke and other clinical events according to APB burden of ectopic beats in a subgroup without permanent AF.
| Endpoint | Incidence rate (per 100 person-year) | HR (95% CI) | p-value | |
|---|---|---|---|---|
| Low APB burden (APB < 5%) | High APB burden (5% ≤ APB) | clinical variable-adjusted** | ||
| Primary endpoint | ||||
| Stroke | 0.76 (0.16–0.22) | 0.94 (0.19–2.74) | 1.20 (0.23–6.08) | 0.824 |
| Other clinical endpoints | ||||
| STE | 0.25 (0.01–1.41) | 0 | — | — |
| All-cause death | 0.76 (0.16–2.21) | 0.63 (0.76–2.26) | 1.19 (0.18–7.72) | 0.855 |
| Composite outcome (Stroke, STE, All-cause death) | 6.95 (3.18–13.2) | 5.44 (2.0–11.9) | 0.85 (0.30–2.42) | 0.764 |
**Adjusted for age, sex, hypertension, diabetes, dyslipidemia, prior stroke/transient ischemic attack, congestive heart failure, prior myocardial infarction/peripheral arterial occlusive disease, and anticoagulant, antiplatelet, statin use.
AF, atrial fibrillation; APB, atrial premature beat; CI, confidence interval; HR, hazard ratio; STE, systemic thromboembolism.