Table 1.

The patient characteristics at the baseline.

Parameter	Mean value			P value
	Placebo subgroup (n = 24)	Treatment subgroup (n = 120)	Entire group (n = 144)
Age, Me (IQR), years	34.8 (23.9–47.6)	30.9 (22.9–35.0)	31.5 (23.3–36.1)	0.20
Male/female, n	12/12	73/47
${\text{Height},}^{\overline{\mathit{X}}}$ ±SD, cm	173.1 ± 8.1	175.4 ± 8.6	175.0 ± 8.5	0.23
Weight, Me (IQR), kg	70.5 (65.0–84.5)	72.5 (66.5–80.5)	72.0 (65.5–81.0)	0.99
Diastolic BP, Me (IQR), mm Hg	80 (70–80)	80 (70–80)	80 (70–80)	0.84
Systolic BP, Me (IQR), mm Hg	120 (110–120)	120 (112.5–120)	120 (110–120)	0.50
HR, Me (IQR), b/min	83.0 ± 5.4	81.7 ± 6.2	81.9 ± 6.0	0.31
T,${}^{\overline{X}}$ ±SD, °С	37.55 ± 0.28	37.44 ± 0.51	37.46 ± 0.31	0.54
$\mathrm{Stool}\mathrm{frequency}{,}^{\overline{X}}$ ±SD, n	7.8 ± 2.1	7.0 ± 2.4	7.1 ± 2.3	0.12
Dose, tablets	12	12	12	1.0

Abbreviations: Me − median; IQR − 27%-75% interquartile range; BP − blood pressure; SD − standard deviation; HR − heart rate; Т − body temperature.