Table 2.

The dynamics of parameter changes on the 1st day of treatment.

Parameter	Mean value		P value
	Placebo group (n = 24)	Treatment group (n = 120)
Weight, Me (IQR), kg	70.5 (65.0–84.5)	73.0 (66.5–80.5)	0.98
DBP, Me (IQR), mm Hg	77.5 (70–80)	80 (70–80)	0.45
SBP, Me (IQR), mm Hg	120 (117.5–120)	120 (117.5–120)*	0.24
$\mathrm{HR}{,}^{\overline{X}}$ ±SD, b/min	74.9 ± 3.3*	74.7 ± 3.8*	0.79
T,${}^{\overline{X}}$ ±SD, °С	36.78 ± 0.30*	36.70 ± 0.22*	0.26
$\mathrm{Acts}{,}^{\overline{X}}$ ±SD, times	5.0 ± 1.9*	3.7 ± 2.3*	<0.001
$\mathrm{Dose}{,}^{\overline{X}}$ ±SD, tablets	13.2 ± 1.9	12.4 ± 1.2	—

Abbreviations: IQR – interquartile range; T – body temperature; Me – median; SBP – systolic blood pressure; DBP – diastolic blood pressure; HR – heart rate; SD – standard deviation.