. 2020 Apr 14;10:6344. doi: 10.1038/s41598-020-62386-0

Table 4.

The dynamics of treatment efficacy changes.

Effect		Abs. (M ± m%)		P value	RR (95% CI)
Effect		Placebo group (n = 24)	IP group (n = 120)	P value	RR (95% CI)
1^st day	Not achieved	23 (95.8 ± 4.1)	61 (50.8 ± 4.6)	<0.001	0.5 (0.4–0.6)
1^st day	Achieved	1 (4.2 ± 4.1)	59 (49.2 ± 4.6)	<0.001	0.5 (0.4–0.6)
2^nd day	Not achieved	12 (50.0 ± 10.2)	25 (20.8 ± 3.7)	0.01	0.4 (0.3–0.7)
2^nd day	Achieved	12 (50.0 ± 10.2)	95 (79.2 ± 3.7)	0.01	0.4 (0.3–0.7)
3^rd day	Not achieved	4 (16.7 ± 7.6)	2 (1.7 ± 1.1)	0.03	0.10 (0.02–0.52)
3^rd day	Achieved	20 (83.3 ± 7.6)	118 (98.3 ± 1.1)	0.03	0.10 (0.02–0.52)
4^th day	Not achieved	—	—	—	—
4^th day	Achieved	24 (100)	120 (100)	—	—

Abbreviations: M – mean; m – standard error of the mean; RR – risk ratio; CI – confidence interval; Abs. – absolute value.