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. 2020 Mar 2;52(3):409–422. doi: 10.1038/s12276-020-0390-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a PROM2 is overexpressed in pancreatic tumor tissues versus normal tissues (NCBI/GEO/GSE16515, P = 0.032). b High expression of PROM2 is correlated with poor overall survival and disease-free survival in pancreatic cancer (P < 0.001, P < 0.001; TCGA, n = 162). c PROM2 protein expression is upregulated in all eight pancreatic cancer cell lines compared with immortal pancreatic ductal epithelial cell (HPDECs). d PROM2 protein is overexpressed in eight pancreatic cancer tissues (T1–T8) versus adjacent tissues of pancreatic cancer (N1, N2). e Representative images of adjacent tissues and tumor tissues stained with the PROM2 antibody by IHC assay. f Correlation between PROM2 expression and overall/disease-free survival (P < 0.001, P < 0.001; n = 93).