Table 2.
Cohort | Patient number | Mean (years) | Median (years) | ||
---|---|---|---|---|---|
Adult ACC | Genotype | CCa | 68 | 45.01 | 45 |
CTb | 18 | 60.1 | 61 | ||
TTc | 6 | 32.67 | 29 | ||
MAF | 0.163 | ||||
p-value (KW) | 0.00019 | ||||
adjusted p-value (Bonferroni) | 0.00114 | ||||
p-value (MWU) (CC vs TT) | 0.0498 | ||||
p-value (MWU) (CC vs CT) | 0.00038 | ||||
p-value (MWU) (TT vs CT) | 0.0041 | ||||
Adult ACC (somatic wild type p53) | Genotype | CC | 50 | 45.34 | 46.5 |
CT | 16 | 60.19 | 61 | ||
TT | 5 | 32 | 26 | ||
MAF | 0.1831 | ||||
p-value (KW) | 0.00075 |
MAF minor allele frequency, KW Kruskal–Wallis, MWU Mann–Whitney U test.
aCC: Homozygous major.
bCT: Heterozygous.
cHomozygous minor.