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. 2020 Apr 14;10:6358. doi: 10.1038/s41598-020-63031-6

Figure 7.

Figure 7

Effect of actinonin on biomechanical properties of the injured rat vaginal wall at the time of vaginal delivery. (A) Stiffness was quantified from the slope of the linear portion of stress-strain curve. Postpartum time points of 3 and 7d after injury are presented. (B) Maximal stress generating capacity in nonpregnant, pregnant, and postpartum animals with or without injury. Data represent mean ± SEM of nonpregnant (n = 8), normal postpartum (n = 8 per time point), injury + PBS (n = 4 at 3 d, n = 8 at 7 d) and injury + actinonin (n = 6 at 3d, n = 8 at 7d). For clarity, positive error bars are shown. Actinonin alone (without injury) did not alter normal recovery (Supplementary Fig. 3). Inj, injury; Uninj, uninjured; NP, nonpregnant; Act, actinonin; PBS, phosphate buffered saline. *Two-way analysis of variance (P < 0.05).