Table 1.
Biomechanical properties of the vaginal wall in nonpregnant controls, late pregnancy (d21), 3–7d after delivery without injury, 3–7d after delivery with injury + PBS, and 3–7d after delivery with injury + actinonin.
| Total Vaginal Weight, mg | Maximal distention mm | Resting diameter mm | |
|---|---|---|---|
| NonpregnantControls, n = 7 | 159 ± 9 | 11.3 ± 1.6 | 9.6 ± 1.2 |
| Pregnant, D21 n = 7 | 201 ± 22* | 20.8 ± 2.1* | 10.2 ± 0.6 |
| Postpartum, 3d Control, n = 7 | 142 ± 24 | 12.4 ± 1.1 | 9.3 ± 0.9 |
| Postpartum, 3d Inj + PBS, n = 4 | 197 ± 13* | 16.5 ± 2.4 | 6.8 ± 0.3 |
| Postpartum, 3d Inj + Act, n = 6 | 168 ± 7 | 14.8 ± 0.5 | 6.8 ± 1.5 |
| Postpartum, 7d Control, n = 7 | 140 ± 10 | 14.5 ± 1.0 | 8.8 ± 0.4 |
| Postpartum, 7d Inj + PBS, n = 8 | 141 ± 5 | 14.7 ± 2.2 | 8.4 ± 1.2 |
| Postpartum, 7d Inj + Act, n = 8 | 161 ± 13 | 16.9 ± 1.1 | 7.8 ± 0.6 |
Mean ± SEM
PBS, phosphate buffered saline; Inj, injury; Act, actinonin.
*p < 0.05 compared with NP and all postpartum time points.