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. 2020 Apr 14;10:6341. doi: 10.1038/s41598-020-62599-3

Table 2.

Reproductive and general health characteristics of study population by above versus below mean digit ratioa.

Characteristic Right Left
2D:4D Digit Ratio 2D:4D Digit Ratio
Total N = 170b <mean ≥mean OR 95% CI/p Total N = 171 <mean ≥mean OR 95% CI/p
Infertilityc 33 (20.0) 19 (20.9) 14 (18.9) 0.88 (0.41–1.91) 33 (19.9) 19 (20.7) 14 (18.9) 0.90 (0.42–1.94)
Bleeding during pregnancy 29 (17.1) 11 (11.8) 18 (23.4) 2.27 (1.00–5.17) 29 (17.0) 11 (11.8) 18 (23.1) 2.24 (0.98–5.08)
Menses characteristics
Age at menarche (years) mean (±SD) 164 12.8 (1.3) 13.2 (1.5) 0.04 165 12.8 (1.4) 13.1 (1.4) 0.21
Cycle length (days)d mean (±SD) 115 29.6 (5.3) 30.8 (17.9) 0.59 116 30.9 (15.9) 29.2 (5.6) 0.47
Menses duration (days)d mean (±SD) 103 5.1 (1.7) 5.1 (1.4) 0.95 103 5.3 (1.7) 4.9 (1.4) 0.29
Menses bleedingd Heavier than normal 12 (7.1) 5 (5.5) 7 (9.1) 1.72 (0.52–5.66) 12 (7.1) 8 (8.8) 4 (5.1) 0.56 (0.16–1.94)
Dysmenorrhead 66 (63.5) 37 (60.7) 29 (67.4) 1.34 (0.59–3.05) 66 (63.5) 33 (55.9) 33 (73.3) 2.17 (0.94–5.00)
General health characteristicse
Anemia 50 (29.6) 27 (29.3) 23 (29.9) 1.03 (0.53–1.99) 50 (29.4) 31 (33.7) 19 (24.4) 0.63 (0.32–1.24)
CVDf 16 (9.4) 7 (7.5) 9 (11.7) 1.63 (0.58–4.59) 16 (9.4) 6 (6.5) 10 (12.8) 2.13 (0.74–6.16)
Thyroid disordersg 21 (12.4) 12 (12.9) 9 (11.7) 0.89 (0.36–2.25) 21 (12.3) 11 (11.8) 10 (12.8) 1.10 (0.44–2.74)
Herpes 22 (12.9) 12 (12.9) 10 (13.0) 1.01 (0.41–2.48) 22 (12.9) 11 (11.8) 11 (14.1) 1.22 (0.50–3.00)
Migraine/Headache 63 (37.3) 35 (38.0) 28 (36.4) 0.93 (0.50–1.74) 63 (37.1) 35 (38.0) 28 (35.9) 0.91 (0.49–1.71)
Faint 17 (10.0) 10 (10.8) 7 (9.1) 0.83 (0.30–2.30) 17 (9.9) 9 (9.7) 8 (10.3) 1.07 (0.39–2.91)
Dizziness 33 (19.4) 20 (21.5) 13 (16.9) 0.74 (0.34–1.61) 33 (19.3) 21 (22.6) 12 (15.4) 0.62 (0.29–1.37)

aAll numbers presented as n (%), unless otherwise stated.

bone outlier was excluded.

cInfertility defined as having at least one of the following: endometriosis, time to pregnancy >1 year, any fertility treatment in current or previous pregnancy.

dIncluding only women who did not use contraceptives in the last year.

eData presented include variables with at least 10% women with the outcome.

fCardiovascular disease (CVD) defined as having at least one of the following: hypertension, cholesterol or triglycerides, congestive heart failure or stroke, hypertension in current pregnancy.

gThyroid disorders defined as having at least one of the following: hypothyroidism or hyperthyroidism throughout life, hypothyroidism, hyperthyroidism or other thyroid disorder in current pregnancy.