Table 5.

Predictive power of selected variables for the composite of morbidity endpoints.

Predictors	Univariable Analysis			Multivariable Analysis
	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value
HMGB1	1.098	1.036–1.164	0.002	1.072	1.002–1.148	0.044
Coronary artery disease	2.753	1.456–5.204	0.002	1.807	0.838–3.899	0.131
Congestive heart failure	2.060	1.114–3.811	0.021	1.390	0.648–2.979	0.398
EuroSCORE II	1.155	1.057–1.262	0.001	1.023	0.912–1.148	0.694
Pre-operative creatinine	2.349	1.494–3.691	<0.001	2.107	1.302–3.409	0.002
Cardiopulmonary bypass time	1.011	1.005–1.017	<0.001	1.010	1.002–1.017	0.009

CI = confidence interval, HMGB1 = high mobility group box 1.