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. 2019 Jun 21;70(9):1875–1881. doi: 10.1093/cid/ciz541

Figure 5.

Figure 5.

Comparison of qPCR to antigen detection. Performance of TsolR13 qPCR, compared to TsAg B158/B60 enzyme-linked immunosorbent assay detection (ApDia), in CSF and plasma/serum samples at the time of active and cured subarachnoid or ventricular neurocysticercosis. Red indicates test positivity; blue indicates test negativity. A, In the CSF, all 17 (100%) of those with active disease were positive by qPCR and TsAg. B, In the CSF of those cured, 14 of 15 (93.3%) samples were negative by qPCR and 12 of 15 (80%) were negative by TsAg. C, In the plasma (qPCR) or serum (TsAg) of those with active disease, 13 of 16 (81.3%) were positive by qPCR and 12 of 16 (75%) by TsAg. D, In those cured, qPCR was negative in 26 of 30 (86.7%) patients and TsAg was negative in 24 of 30 (80%) patients. Note that 1 active CSF and 3 cured CSF samples were not available for TsAg testing, so were excluded from this comparison. Abbreviations: CSF, cerebral spinal fluid; qPCR, quantitative polymerase chain reaction; TsAg, Taenia solium antigen.