Figure 3.

Correlation of the expression of 2 genes, cereblon (CRBN) and its related gene (IKZF1, IKZF3, or KPNA2) with the relevance to the duration of survival of multiple myeloma patients by lenalidomide plus dexamethasone therapy. All patient samples were divided into 4 groups according to their expression of the respective pair of genes, ie, CRBN and each related gene. A‐C, Comparison of progression‐free survival (PFS, left panels) and overall survival (OS, right panels) between 4 groups are shown in each graph. D, Linear regression model showing the relationship between low levels of IKZF1 and high levels of KPNA2