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ACE2 receptors are expressed in multiple organs, with the greatest density and potential for upregulation in the lungs, heart and blood vessels (arteries and veins; macrovessels and microvessels). There is a direct relationship between ACE2 receptor density and target organ involvement and injury among patients with COVID-19
From Zou X. Front Med 10.1007/s11684-020-0754-0 with permission
