Table 3.
Univariate and multivariate logistic regression analysis on microRNA (miR)‐92b‐3p expression levels with overall survival in validation cohort (n = 75)
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (<65 vs. ≥65 y) | 0.76 | 0.35‐1.68 | .500 | — | — | — |
| TNM stage (I, II vs. III, IV) | 0.46 | 0.21‐1.01 | .053 | 0.43 | 0.18‐0.99 | .048 |
| Grade (G1, 2 vs. G3) | 0.43 | 0.18‐1.00 | .050 | 0.60 | 0.24‐1.45 | .250 |
| Vascular invasion (− vs. +) | 0.79 | 0.31‐2.00 | .620 | — | — | — |
| Na (<139 vs. ≥139) (mEq/L) | 0.69 | 0.27‐1.73 | .430 | — | — | — |
| NLR (<2.52 vs. ≥2.52) | 0.79 | 0.36‐1.74 | .560 | — | — | — |
| PLR (<1.76 vs. ≥1.76) | 0.76 | 0.34‐1.70 | .500 | — | — | — |
| CRP (<1 mg/dL vs. ≥1 mg/dL) | 0.77 | 0.30‐1.95 | .580 | — | — | — |
| miR‐92b‐3p (high vs. low) | 2.56 | 1.10‐5.97 | .030 | 2.86 | 1.20‐6.83 | .018 |
Abbreviations: CI, confidence interval; CRP, C‐reactive protein; HR, hazard ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio.