Table 1.
Association of anthrax toxin receptor 1 (ANTXR1) expression with clinicopathologic parameters of gastric cancer (GC) patients
| Characteristics | Total (n = 103) | ANTXR1 protein expression | P value | |
|---|---|---|---|---|
| Low (n = 37) | High (n = 66) | |||
| Age (y) | ||||
| ≤60 | 46 | 15 | 31 | .529 |
| >60 | 57 | 22 | 35 | |
| Gender | ||||
| Male | 63 | 20 | 43 | .268 |
| Female | 40 | 17 | 23 | |
| Differentiation | ||||
| Well + moderate | 41 | 18 | 23 | .170 |
| Poor | 62 | 19 | 43 | |
| T classification | ||||
| T1 + T2 | 32 | 19 | 13 | .001 |
| T3 + T4 | 71 | 18 | 53 | |
| Lymph node metastasis | ||||
| N0 | 38 | 21 | 17 | .002 |
| N1‐3 | 65 | 16 | 49 | |
| Distant metastasis | ||||
| M0 | 82 | 33 | 49 | .071 |
| M1 | 21 | 4 | 17 | |
| AJCC stage | ||||
| I + II | 35 | 23 | 12 | <.001 |
| III + IV | 68 | 14 | 54 | |
Results showed 64.08% (66/103) in GC tissue indicated a relatively higher level of ANTXR1 compared with 31.07% (32/103) in the matched adjacent normal tissue. AJCC, American Joint Committee on Cancer.