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. 2009 Jan 21;2009(1):CD003799. doi: 10.1002/14651858.CD003799.pub2

Birge 1997.

Methods Design: 
 randomized,placebo‐ controlled, double‐blind 
 parallel groups 
 9 months
Participants Country: U.S.A. 
 n=20 DAT (DSM?), mild dementia (CDRS <2) 
 Aged 77 (SD 6, 67‐86). Exclusion criteria: Depression (GDS >5), age < 70, Other types of dementia syndromes
Interventions 1. CEE oral 0.625 mg/day + MPA 5 mg for 15 days every 3rd mth 
 2. Placebo
Outcomes General (BIMC) 
 Memory (CERAD word list, Paired Associates, Digit Span), Speed (TMT), Other (Clock drawing)
Notes HRT >placebo: on Paired associate, Placebo > HRT: on BMIC, Digit Span 1/6 tests