Zhang 2006.
| Methods | Design:
randomised, double‐blind, parallel groups 4 months |
|
| Participants | Country: China n=41 mild AD (DSM‐IV) Aged 47‐62 (55 +/‐0.4) years All menopause before age 65 Exclusion:dementia due to 'vessel, infection, toxication, metabolism, liver/kidney dysfunction or depression. All gave informed consent and had CT/MRI | |
| Interventions | 1. Beimeili (conjugated estrogen, Wyeth, USA) oral/1.25 mg /day 2. vit B1 20 mg 3x/day as Placebo | |
| Outcomes | General Hasegawa Dementia Scale‐R (HDS‐R) ADL | |
| Notes | HRT > vitamin B1 after 4 months on HDS‐R and ADL | |