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. 2012 Sep 12;2012(9):CD003853. doi: 10.1002/14651858.CD003853.pub3

Podoshin 1995.

Methods 4‐arm, randomised controlled trial
No detail on randomisation method is given
Participants 225 adults (in total) with idiopathic subjective tinnitus (83 in the amitriptyline group, 40 in control (placebo) group)
Interventions Administration of amitriptyline (10 mg 3 times daily) or placebo (1 tablet 3 times daily) for 10 weeks
Outcomes Improvement in degree of tinnitus at rest and during activity (by questionnaire and audiometry) at 10 weeks
Notes Only 2 of the 4 treatment arms (amitriptyline and placebo) were relevant to this review. The 2 other treatment arms were biofeedback (62 participants) versus control (40 participants)
Results were mainly presented graphically
Overall methodological quality: C