Aydemir 2011a.

Methods	Randomised controlled trial
Participants	184 VLBW infants
Interventions	Fluconazole 3 mg/kg (N = 93) every third day versus normal saline placebo (N = 91) until the 30th day after birth (or 45th day in ELBW infants)
Outcomes	Fungal colonisation and invasive infection Death prior to hospital discharge Emergence of fungi with native azole resistance Adverse drug reactions
Notes	Setting: Zekai Tahir Burak Maternity Hospital, Ankara, Turkey; 2008 to 2009
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	Computer‐generated
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Report states placebo‐controlled but unclear how this was achieved
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Report states placebo‐controlled but unclear how this was achieved
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Report states placebo‐controlled but unclear how this was achieved
Incomplete outcome data (attrition bias) All outcomes	Low risk	Complete follow‐up