Comparison 13. Risk of bias subgroup analysis: selection of outcome.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Selection of outcome: primary trial outcome clearly indicated	31	4775	Risk Ratio (M‐H, Random, 95% CI)	0.93 [0.86, 1.00]
2 Selection of outcome: primary trial outcome not clearly indicated (or not selected)	13	1265	Risk Ratio (M‐H, Random, 95% CI)	0.95 [0.89, 1.01]
3 Selection of outcome: primary trial outcome clearly indicated	85	6028	Std. Mean Difference (IV, Random, 95% CI)	‐0.26 [‐0.34, ‐0.19]
4 Selection of outcome: primary trial outcome not clearly indicated (or not selected)	73	4485	Std. Mean Difference (IV, Random, 95% CI)	‐0.17 [‐0.25, ‐0.09]