| Methods |
Design: three group parallel trial
Purpose: examine the effect of investigating cardiovascular parameters in cancer patients receiving antiemetic cannabis treatment |
| Participants |
Patients: cancer patients receiving nausea inducing chemotherapy
Baseline comparability: NS |
| Interventions |
Placebo: NS
Untreated: no placebo or cannabis
Experimental:
‐cannabis (three doses)
‐prochlorperazine
(Co‐intervention: yes, chemotherapy) |
| Outcomes |
Emetic events
Psychological events
Heart rate
Blood pressure
Intraocular pressure |
| Notes |
Relevant outcome data not accessible |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
NS |
| Allocation concealment? |
Unclear risk |
NS |
| Blinding?
Treatment provider |
Unclear risk |
NS |
| Blinding?
Outcome assessor |
Unclear risk |
NS |
| Incomplete outcome data addressed?
All outcomes |
High risk |
Drop‐out > 15% or NS |
| Free of selective reporting? |
High risk |
Relevant outcome data not accessible |
| Free of other bias? |
Low risk |
|
| Trial size > 49? |
High risk |
N = 48 |
| Clearly concealed allocation + trial size > 49 + drop‐out max 15% |
High risk |
Trial size < 49 |
