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. 2010 Jan 20;2010(1):CD003974. doi: 10.1002/14651858.CD003974.pub3

Pelham 1992.

Methods Design: three group, multi‐period cross‐over trial (number of periods NS) 
 Purpose: examine the perception of what influenced mood and behaviour (causal attribution) in boys treated for attention deficit hyperactivity disorder by methylphenidate or placebo
Participants Patients: boys with attention deficit hyperactivity disorder attending a summer camp 
 Baseline comparability: not relevant
Interventions Placebo: tablet with no methylphenidate 
 Untreated: no tablet 
 Experimental: tablet with methylphenidate 
 (Co‐intervention: 
 ‐summer camp treatment program (behavioural therapy principles) 
 ‐same boys also participated in trials with other drugs on days not included in the present study)
Outcomes Behaviour rating scales, including ratings of "Did you have a good day?" 
 Attribution rating scales (what the children themselves thought influenced behaviour or mood) 
 Mood/self‐esteem rating scales 
 Forced‐Choice Questions
Notes The outcome data was not available from the first period only, and was calculated as deriving from a parallel group trial.
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk NS
Allocation concealment? Unclear risk NS
Blinding? 
 Treatment provider Low risk '... designed to examine ADHD boys' causal attributions in a double‐blind, within‐subject, placebo‐controlled medication trial'
Blinding? 
 Outcome assessor Unclear risk Not relevant as patient reported outcome
Incomplete outcome data addressed? 
 All outcomes High risk Drop‐out > 15% or NS
Free of selective reporting? Unclear risk No protocol available
Free of other bias? Low risk  
No signs of variance inequality or skewness? Low risk No variance inequality (F‐test not statistically significant) and no skewness (1.64 standard deviations does not exceed the mean)
Trial size > 49? Low risk N = 76
Clearly concealed allocation + trial size > 49 + drop‐out max 15% High risk Drop‐out > 15% or NS