| Methods |
Design: three group parallel trial
Purpose: examine the effect of promazine on the behaviour of chronic schizophrenics |
| Participants |
Patients: woman chronic schizophrenic in‐patients
Baseline comparability: yes |
| Interventions |
Placebo: capsule with no promazine
Untreated: no capsule
Experimental: capsule with promazine
(Co‐intervention: no) |
| Outcomes |
Behaviour change on Gardner Behavior Chart |
| Notes |
Relevant outcome data not accessible |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
NS |
| Allocation concealment? |
Unclear risk |
NS |
| Blinding?
Treatment provider |
Low risk |
'The double‐blind technique was employed throughout the study' |
| Blinding?
Outcome assessor |
Low risk |
'Those attendants who rated the patients' behavioral adjustment did not dispense medication and were unaware of the experimental group to which a patient was assigned' |
| Incomplete outcome data addressed?
All outcomes |
High risk |
Drop‐out > 15% or NS |
| Free of selective reporting? |
High risk |
Relevant outcome data not accessible |
| Free of other bias? |
Low risk |
|
| Trial size > 49? |
Low risk |
N = 62 |
| Clearly concealed allocation + trial size > 49 + drop‐out max 15% |
High risk |
Allocation not clearly concealed |
