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. 2010 Jan 20;2010(1):CD003974. doi: 10.1002/14651858.CD003974.pub3

Tsay 2004.

Methods Design: three group parallel trial 
 Purpose: examine the effect of acupressure on fatigue in patients with end‐stage renal disease
Participants Patients: patients with end‐stage renal disease 
 Baseline comparability: yes
Interventions Placebo: acupressure on sites not regarded acupressure sites 
 Untreated: no acupressure 
 Experimental: acupressure on sites regarded acupressure sites 
 (Co‐intervention: standard medical care)
Outcomes Revised Piper fatigue Scale 
 Fatigue (100 mm VAS) 
 Pittsburgh Sleep Quality Index 
 Beck Depression Inventory
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Blinding? 
 Outcome assessor Unclear risk Not relevant as patient reported outcome
Incomplete outcome data addressed? 
 All outcomes High risk  
Free of selective reporting? Unclear risk No protocol available
Free of other bias? Low risk  
No signs of variance inequality or skewness? Low risk No variance inequality (F‐test not statistically significant) and no skewness (1.64 standard deviations does not exceed the mean)
Trial size > 49? Low risk N = 71
Clearly concealed allocation + trial size > 49 + drop‐out max 15% High risk