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. 2010 Jan 20;2010(1):CD003974. doi: 10.1002/14651858.CD003974.pub3

Etringer 1982.

Methods Design: three group parallel trial 
 Purpose: examine the effect of 'participant modelling' (snake handling) therapy on snake phobia
Participants Patients: individuals who were unable to hold a snake for 10 sec 
 Baseline comparability: yes
Interventions Placebo: sessions of 'graduated subliminal modelling'. Patients were exposed to blank slides and told they were subliminal pictures of snakes. 
 Untreated: no sessions 
 Experimental: sessions of 'participant modelling' 
 (Co‐intervention: NS)
Outcomes Behavioral avoidance test (18 successive steps of snake interaction tasks). Fear arousal accompanying approach. Anticipatory fear. Self‐efficacy expectations
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk NS
Allocation concealment? Unclear risk NS
Blinding? 
 Treatment provider High risk Not described as double‐blind (placebo/participant modelling)
Blinding? 
 Outcome assessor Low risk 'The assessors were kept blind as to each subject's particular treatment condition'
Incomplete outcome data addressed? 
 All outcomes Low risk Drop‐out < 15%
Free of selective reporting? Unclear risk No protocol available
Free of other bias? Low risk  
No signs of variance inequality or skewness? Low risk No variance inequality (F‐test not statistically significant) and no skewness (1.64 standard deviations does not exceed the mean)
Trial size > 49? High risk N = 25
Clearly concealed allocation + trial size > 49 + drop‐out max 15% High risk Trial size < 49