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. 2008 Oct 8;2008(4):CD003823. doi: 10.1002/14651858.CD003823.pub2

Comparison 1. Benazepril vs Placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Change in trough SBP 7   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.1 2 mg 1 36 Mean Difference (IV, Fixed, 95% CI) 0.20 [‐11.87, 12.27]
1.2 4 mg 1 71 Mean Difference (IV, Fixed, 95% CI) ‐5.5 [‐12.17, 1.17]
1.3 5 mg 2 60 Mean Difference (IV, Fixed, 95% CI) ‐6.52 [‐16.09, 3.06]
1.4 10 mg 3 284 Mean Difference (IV, Fixed, 95% CI) ‐2.68 [‐5.98, 0.61]
1.5 20 mg 6 422 Mean Difference (IV, Fixed, 95% CI) ‐8.30 [‐11.14, ‐5.46]
1.6 40 mg (Max Dose) 2 74 Mean Difference (IV, Fixed, 95% CI) ‐8.68 [‐14.00, ‐1.35]
1.7 80 mg 1 50 Mean Difference (IV, Fixed, 95% CI) ‐11.40 [‐19.95, ‐2.85]
2 Change in trough DBP 7   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.1 2 mg 1 36 Mean Difference (IV, Fixed, 95% CI) 1.1 [‐6.54, 8.74]
2.2 4 mg 1 71 Mean Difference (IV, Fixed, 95% CI) ‐4.10 [‐7.95, ‐0.25]
2.3 5 mg 2 60 Mean Difference (IV, Fixed, 95% CI) ‐2.04 [‐8.60, 4.53]
2.4 10 mg 3 283 Mean Difference (IV, Fixed, 95% CI) ‐0.72 [‐2.67, 1.22]
2.5 20 mg 6 422 Mean Difference (IV, Fixed, 95% CI) ‐4.53 [‐6.14, ‐2.93]
2.6 40 mg (Max Dose) 2 74 Mean Difference (IV, Fixed, 95% CI) ‐4.73 [‐9.15, ‐0.31]
2.7 80 mg 1 51 Mean Difference (IV, Fixed, 95% CI) ‐6.80 [‐11.60, 0.00]