Comparison 5. Fosinopril vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	6		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 2.5 mg	1	38	Mean Difference (IV, Fixed, 95% CI)	‐2.9 [‐13.01, 7.21]
1.2 5 mg	1	94	Mean Difference (IV, Fixed, 95% CI)	‐3.70 [‐10.37, 2.97]
1.3 10 mg	3	151	Mean Difference (IV, Fixed, 95% CI)	‐3.86 [‐9.03, 1.30]
1.4 20 mg	5	208	Mean Difference (IV, Fixed, 95% CI)	‐9.26 [‐13.72, ‐4.79]
1.5 40 mg (Max Dose)	3	158	Mean Difference (IV, Fixed, 95% CI)	‐7.81 [‐12.91, ‐2.72]
2 Change in trough DBP	6		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 2.5 mg	1	39	Mean Difference (IV, Fixed, 95% CI)	‐0.70 [‐6.31, 4.91]
2.2 5 mg	1	93	Mean Difference (IV, Fixed, 95% CI)	‐3.20 [‐7.12, 0.72]
2.3 10 mg	3	151	Mean Difference (IV, Fixed, 95% CI)	‐3.45 [‐6.42, ‐0.47]
2.4 20 mg	5	209	Mean Difference (IV, Fixed, 95% CI)	‐7.79 [‐10.12, ‐5.46]
2.5 40 mg (Max Dose)	3	157	Mean Difference (IV, Fixed, 95% CI)	‐4.73 [‐7.69, ‐1.76]