Comparison 7. Lisinopril vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	5		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 1.25 mg	1	46	Mean Difference (IV, Fixed, 95% CI)	3.2 [‐5.00, 13.40]
1.2 5 mg	1	47	Mean Difference (IV, Fixed, 95% CI)	‐2.0 [‐13.22, 9.22]
1.3 10 mg	4	648	Mean Difference (IV, Fixed, 95% CI)	‐7.75 [‐9.98, ‐5.51]
1.4 20 mg	1	50	Mean Difference (IV, Fixed, 95% CI)	‐7.80 [‐18.67, 3.07]
1.5 80 mg (Max Dose)	1	50	Mean Difference (IV, Fixed, 95% CI)	‐13.8 [‐24.46, ‐3.14]
2 Change in trough DBP	5		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 1.25 mg	1	46	Mean Difference (IV, Fixed, 95% CI)	2.8 [‐2.34, 7.94]
2.2 5 mg	1	47	Mean Difference (IV, Fixed, 95% CI)	0.0 [‐5.32, 5.32]
2.3 10 mg	4	648	Mean Difference (IV, Fixed, 95% CI)	‐4.71 [‐5.92, ‐3.50]
2.4 20 mg	1	51	Mean Difference (IV, Fixed, 95% CI)	‐4.6 [‐10.17, 0.97]
2.5 80 mg (Max Dose)	1	49	Mean Difference (IV, Fixed, 95% CI)	‐6.00 [‐11.72, ‐0.28]