| 1 Change in trough SBP |
7 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 1.1 2 mg |
1 |
36 |
Mean Difference (IV, Fixed, 95% CI) |
0.20 [‐11.87, 12.27] |
| 1.2 4 mg |
1 |
71 |
Mean Difference (IV, Fixed, 95% CI) |
‐5.5 [‐12.17, 1.17] |
| 1.3 5 mg |
2 |
60 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.52 [‐16.09, 3.06] |
| 1.4 10 mg |
3 |
284 |
Mean Difference (IV, Fixed, 95% CI) |
‐2.68 [‐5.98, 0.61] |
| 1.5 20 mg |
6 |
422 |
Mean Difference (IV, Fixed, 95% CI) |
‐8.30 [‐11.14, ‐5.46] |
| 1.6 40 mg (Max Dose) |
2 |
74 |
Mean Difference (IV, Fixed, 95% CI) |
‐8.68 [‐14.00, ‐1.35] |
| 1.7 80 mg |
1 |
50 |
Mean Difference (IV, Fixed, 95% CI) |
‐11.40 [‐19.95, ‐2.85] |
| 2 Change in trough DBP |
7 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 2.1 2 mg |
1 |
36 |
Mean Difference (IV, Fixed, 95% CI) |
1.1 [‐6.54, 8.74] |
| 2.2 4 mg |
1 |
71 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.10 [‐7.95, ‐0.25] |
| 2.3 5 mg |
2 |
60 |
Mean Difference (IV, Fixed, 95% CI) |
‐2.04 [‐8.60, 4.53] |
| 2.4 10 mg |
3 |
283 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.72 [‐2.67, 1.22] |
| 2.5 20 mg |
6 |
422 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.53 [‐6.14, ‐2.93] |
| 2.6 40 mg (Max Dose) |
2 |
74 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.73 [‐9.15, ‐0.31] |
| 2.7 80 mg |
1 |
51 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.80 [‐11.60, 0.00] |