Comparison 9. Perindopril vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	6		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 2 mg	2	85	Mean Difference (IV, Fixed, 95% CI)	‐3.24 [‐13.20, 6.72]
1.2 4 mg	6	820	Mean Difference (IV, Fixed, 95% CI)	‐6.76 [‐9.41, ‐4.12]
1.3 8 mg (Max Dose)	2	82	Mean Difference (IV, Fixed, 95% CI)	‐9.81 [‐19.32, ‐0.31]
1.4 16 mg	1	67	Mean Difference (IV, Fixed, 95% CI)	‐8.9 [‐19.65, 1.85]
2 Change in trough DBP	6		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 2 mg	2	85	Mean Difference (IV, Fixed, 95% CI)	‐2.10 [‐6.40, 2.20]
2.2 4 mg	6	820	Mean Difference (IV, Fixed, 95% CI)	‐4.91 [‐6.21, ‐3.61]
2.3 8 mg (Max Dose)	2	82	Mean Difference (IV, Fixed, 95% CI)	‐5.81 [‐10.11, ‐1.52]
2.4 16 mg	1	67	Mean Difference (IV, Fixed, 95% CI)	‐5.50 [‐10.09, ‐0.91]