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| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Change in trough SBP | 3 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 1.1 20 mg | 3 | 196 | Mean Difference (IV, Fixed, 95% CI) | ‐5.87 [‐9.75, ‐1.99] |
| 2 Change in trough DBP | 3 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 2.1 20 mg | 3 | 196 | Mean Difference (IV, Fixed, 95% CI) | ‐3.26 [‐5.85, ‐0.68] |
