Comparison 15. 1/16 Max Dose vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	4	262	Mean Difference (IV, Fixed, 95% CI)	‐0.16 [‐3.78, 3.46]
1.1 Fosinopril 2.5 mg	1	58	Mean Difference (IV, Fixed, 95% CI)	‐2.9 [‐9.93, 4.13]
1.2 Lisinopril 5 mg	1	76	Mean Difference (IV, Fixed, 95% CI)	‐2.0 [‐9.79, 5.79]
1.3 Ramipril 1.25 mg	2	128	Mean Difference (IV, Fixed, 95% CI)	2.01 [‐3.02, 7.05]
2 Change in trough DBP	4	262	Mean Difference (IV, Fixed, 95% CI)	0.15 [‐1.86, 2.16]
2.1 Fosinopril 2.5 mg	1	58	Mean Difference (IV, Fixed, 95% CI)	‐0.70 [‐4.77, 3.37]
2.2 Lisinopril 5 mg	1	76	Mean Difference (IV, Fixed, 95% CI)	0.0 [‐3.68, 3.68]
2.3 Ramipril 1.25 mg	2	128	Mean Difference (IV, Fixed, 95% CI)	0.70 [‐2.28, 3.67]