2. Summary of the blood pressure lowering efficacy of ACE inhibitors.

ACE Inhibitor	Lowest effective dose (mg/day)	Lowest dose with near maximal BP lowering (mg/day)	Near maximal trough SBP lowering (mm Hg), 95% CI	Near maximal trough DBP lowering (mm Hg), 95% CI
benazepril	20	20	‐8.70 (‐11.43, ‐5.97)	‐4.92 (‐6.47, ‐3.36)
captopril	37.5	37.5	‐9.68 (‐11.73, ‐7.63)	‐5.43 (‐6.47, ‐4.40)
cilazapril	2.5	2.5	‐5.58 (‐7.84, ‐3.32)	‐3.50 (‐4.40, ‐2.60)
enalapril	5	20	‐8.66 (‐10.48, ‐6.84)	‐4.80 (‐5.81, ‐3.79)
fosinopril	10‐20	20	‐7.62 (‐11.07, ‐4.17)	‐5.00 (‐6.94, ‐3.05)
imidapril	Not estimable	Not estimable	‐9.30 (‐14.83, ‐3.78)	‐5.76 (‐9.44, ‐2.07)
lisinopril	10	10	‐8.00 (‐10.14, ‐5.85)	‐4.76 (‐5.92, ‐3.60)
moexipril	15	Not estimable	‐8.45 (‐11.99, ‐4.91)	‐4.38 (‐6.29, ‐2.46)
perindopril	4	4	‐7.09 (‐9.56, ‐4.61)	‐5.02 (‐6.22, ‐3.82)
quinapril	Not estimable	Not estimable	‐7.05 (‐11.26, ‐2.84)	‐3.35 (‐5.98, ‐0.72)
ramipril	5	5	‐6.29 (‐9.26, ‐3.32)	‐4.14 (‐5.81, ‐2.48)
spirapril	3‐6	6	‐8.54 (‐11.18, ‐5.89)	‐6.08( ‐7.50, ‐4.66)
temocapril	Not estimable	Not estimable	‐10.00 (‐23.87, 3.87)	‐5.00 (‐13.34, 3.34)
trandolapril	1	1	‐7.31 (‐8.85, ‐5.77)	‐4.42 (‐5.24, ‐3.60)