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| Proportion of recommended maximum dose (Max) | Number of studies | Weighted mean change from baseline in pulse pressure (95% CI) | |
| ACE inhibitors | 1/8 Max | 18 | ‐1.2 (‐2.0, ‐0.4) |
| 1/4 Max | 40 | ‐1.8 (‐2.6, ‐0.9) | |
| 1/2 Max | 50 | ‐2.5 (‐3.2, ‐1.9) | |
| Max | 16 | ‐3.7 (‐5.5, ‐1.9) | |
| 2 Max | 6 | ‐4.1 (‐6.3, ‐1.9) | |
| 1/2 Max and above | 54 | ‐2.9 (‐3.5, ‐2.3) | |
| Placebo | 74 | 0.6 (0.1, 1.1) |
